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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PECAM1
All Species:
14.55
Human Site:
S587
Identified Species:
35.56
UniProt:
P16284
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16284
NP_000433.3
738
82536
S587
H
A
S
S
V
P
R
S
K
I
L
T
V
R
V
Chimpanzee
Pan troglodytes
XP_511582
738
82461
S587
H
A
S
S
V
P
R
S
K
I
L
T
V
R
V
Rhesus Macaque
Macaca mulatta
XP_001116549
727
80984
S587
H
A
S
S
V
P
R
S
K
I
L
T
V
R
V
Dog
Lupus familis
XP_853419
738
82732
N587
L
K
S
S
P
Q
S
N
V
L
T
V
R
V
F
Cat
Felis silvestris
Mouse
Mus musculus
Q08481
727
81244
S576
S
M
R
T
S
P
R
S
S
T
L
A
V
R
V
Rat
Rattus norvegicus
Q3SWT0
678
76171
K553
W
H
H
E
Q
T
S
K
E
Q
E
G
Q
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510863
738
82529
S569
S
N
Q
K
V
P
R
S
S
L
I
T
V
K
V
Chicken
Gallus gallus
XP_001234536
405
45647
E280
I
L
T
A
S
M
N
E
L
D
E
H
K
E
L
Frog
Xenopus laevis
NP_001089003
727
80227
E590
A
H
Q
T
V
D
S
E
H
I
Y
V
K
A
V
Zebra Danio
Brachydanio rerio
XP_697859
765
84632
A598
E
T
K
Q
S
K
P
A
R
I
G
V
S
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
89.8
72.2
N.A.
63
61.1
N.A.
50.9
21.5
29.9
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
94.3
84
N.A.
78.4
75.4
N.A.
68.2
34.1
51.7
47
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
46.6
0
N.A.
46.6
0
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
53.3
6.6
N.A.
66.6
20
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
30
0
10
0
0
0
10
0
0
0
10
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% D
% Glu:
10
0
0
10
0
0
0
20
10
0
20
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% G
% His:
30
20
10
0
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
50
10
0
0
0
0
% I
% Lys:
0
10
10
10
0
10
0
10
30
0
0
0
20
10
0
% K
% Leu:
10
10
0
0
0
0
0
0
10
20
40
0
0
10
10
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
50
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
10
10
10
0
0
0
10
0
0
10
0
0
% Q
% Arg:
0
0
10
0
0
0
50
0
10
0
0
0
10
40
0
% R
% Ser:
20
0
40
40
30
0
30
50
20
0
0
0
10
0
0
% S
% Thr:
0
10
10
20
0
10
0
0
0
10
10
40
0
0
0
% T
% Val:
0
0
0
0
50
0
0
0
10
0
0
30
50
10
60
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _